Recent research finding

No.31 Enhancement of Adiponectin Production by Addition of CoQ10-γCD Complex



Metabolic syndrome becomes an object of public concern, so using of health foods or supplements as alternative medicine and preventive medicine is very efficient in an aged society.
Coenzyme Q10 (CoQ10) is one of remarkable food constituents. It's a important coenzyme for energy production in the living body, and known as powerful antioxidant. However, it isn't absorbed well into the body due to its low water solubility. Therefore, we examined the bioavailability enhancement of CoQ10 by complexation with γ-cyclodextrin (γCD).
In this study, we estimated the generated amount of adiponectin by addition of CoQ10-γCD complex. The adiponectin is one of good adipokines secreted from the adipose cells, its abnormal secretion is associated with sideration of metabolic syndrome. Therefore, it's ever so important the measurement of adiponectin.

Adiponectin (Good Adipokine)

● 田村 信司, アディポサイトカインの概念, 日内会誌, 95, 87-93 (2006).

● 門脇 孝, 山内敏正, 窪田直人,アディポネクチンと糖尿病・心血管病の分子メカニズム,第128回 日本医学会シンポジウム記録集,糖尿病と動脈硬化, 34-45 (2004).

Measurement of Adiponectin Concentration